Logo Normandie Logo Europe Logo de La Manche

Antifouling activities of immobilized ferrocenyl glucose on glassy carbon surface

Résumé : Polar coatings are used to protect surfaces from marine fouling based on the formation of a hydrated surface layer which acts as a barrier to marine microorganisms. In this context, we have developed a material with glucose bound to a ferrocene to prevent surface absorption. Glucose brings the polarity while the ferrocene has the role of varying the state of charge of the surface. We therefore describe the synthesis of 6-deoxy-6-(4-ferrocenyl-1H-1,2,3-triazol-1-yl)-1-(4-aminophenyl)--D-glucopyranose 6, its immobilization on the surface of a C electrode and develop the methodology used for anti-bacterial testing. We were able to demonstrate that the immobilization of glucose 6 could be done in an artificial seawater environment by oxidation of an amine. The use of a 96 micro-well platform equipped with electrodes for cyclic voltammetry, linked to a potentiostat, allowed the electrical solicitation of the coating in the presence of marine bacteria with a greater number of biological replicates. We have shown that the coating has an antibacterial effect and this effect is accentuated when the coating is electrically stressed resulting in the appearance and disappearance of charge on the ferrocene, a phenomenon that seems to be conducive to colonization by bacteria.
Domaine de référence : Antifouling
Auteur Peigneguy Fanny, Cougnon Charles, Barry-Martinet Raphaëlle, Bressy Christine, Gohier Frederic
Année de parution : 2020.
Type de document : Article de revue.
Exporter la référence : BibTeX | Zotero RDF | RIS (EndNote)

Ce projet est financé par le Fonds Européen de Développement Régional, la Région Normandie et le Conseil Départemental de la Manche.