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@article{xu_sensing_2020, title = {Sensing the unreachable: challenges and opportunities in biofilm detection}, volume = {64}, issn = {0958-1669}, shorttitle = {Sensing the unreachable}, url = {http://www.sciencedirect.com/science/article/pii/S0958166919301089}, doi = {10.1016/j.copbio.2019.10.009}, abstract = {Bacteria can attach to essentially all materials and form multicellular biofilms with high-level tolerance to antimicrobials. Detrimental biofilms are responsible for a variety of problems ranging from food and water contamination, bio-corrosion, to drug resistant infections. Besides the challenges in control, biofilms are also difficult to detect due to the lack of biofilm-specific biomarkers and methods for non-destructive imaging. In this article, we present a concise review of recent advancements in this field, with a focus on medical device-associated infections. We also discuss the technologies that have potential for non-destructive detection of bacterial biofilms.}, language = {en}, urldate = {2019-11-25}, journal = {Current Opinion in Biotechnology}, author = {Xu, Yikang and Dhaouadi, Yousr and Stoodley, Paul and Ren, Dacheng}, month = aug, year = {2020}, pages = {79--84}, }